名稱 | AI-Edigene® NRAS p.G12S Reference Standard Pl |
型號 | CBP10528 |
報價 | ![]() |
特點 | AI-Edigene® NRAS p.G12S Reference Standard Plus |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10528AI-Edigene® NRAS p.G12S Reference Standard Pl

- 詳細(xì)內(nèi)容
CBP10528 | |
Format | Genomic DNA |
Description | NRAS G12S is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G12S confers a loss of function on Nras protein as indicated by increased Erk phosphorylation, increased cell preliferation, and is transforming in culture (PMID: 17823240). |
Technical Data | |
DNA Change: | c.34G>A |
AA Change | p.G12S |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | NM_002524.5 |
Cosmic ID | COSM563 |
Chr position(GRCh37) | chr1:115258748 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purity | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |